Based on characters created by best-selling crime novelist Tess Gerritsen, RIZZOLI & ISLES stars Angie Harmon as Jane Rizzoli, a tough-as-nails Boston police detective, and Sasha Alexander as Maura Isles, a smart, impeccably dressed medical examiner from a privileged background. Despite being complete opposites, the two women share an offbeat chemistry and strong working relationship that has helped them bust some of Boston's most notorious criminals.